Mission Garden is a living agricultural museum of Sonoran Desert-adapted heritage fruit trees, traditional local heirloom crops and edible native plants. The Garden is managed by Friends of Tucson's Birthplace, a 501(c)3 non-profit with no religious affiliation. Mission Garden is located at the foot of Sentinel Peak, at the site of the Native American village of S-cuk Son (pronounced Chuk Shon), a place sacred to the Tohono O’odham.

Mission Garden’s primary mission is to preserve, transmit and revive the region’s rich agricultural heritage by growing garden plots representative of more than 4000 years of continuous cultivation in the Tucson Basin.